Short answer: if you are replacing Roche TriPure Isolation Reagent, the closest like-for-like option is CHANGYU TRIpure Reagent (CYRN01) — the same single-phase phenol–guanidine chemistry for total RNA, DNA and protein. If you prefer to skip phase separation, the CYRN03 RNApure Total RNA Kit combines TRIzol-style lysis with a spin column.
This page is for researchers searching for TriPure isolation reagent — the phenol–guanidine single-phase RNA isolation chemistry also known as the TRIzol family. Changyu Bio supplies TRIzol-style total RNA purification kits: the CYRN03 RNApure Total RNA Kit combines TRIzol-style Buffer RL lysis with silica spin-column purification in one workflow. Brand names identify catalog items only; Changyu Bio is not an authorized Roche or Thermo Fisher distributor. Research Use Only.
Looking for a TRIzol alternative? See CHANGYU TRIpure Reagent – RIN 8.7 vs 8.6 in a side-by-side test.
What TriPure isolation reagent is
TriPure Isolation Reagent (Roche) is a ready-to-use monophasic solution of phenol and guanidine thiocyanate that simultaneously isolates RNA, DNA, and protein from one sample. It belongs to the same chemistry family as TRIzol (Thermo Fisher). Researchers who search for tripure, tripure isolation reagent, tripure rna, tripure reagent composition, or trizol tripure are usually comparing single-phase RNA extraction reagents for tissues and cultured cells.
Changyu option: CYRN03 RNApure Total RNA Kit
| Catalog number | CYRN03 |
| Product | RNApure Total RNA Kit |
| Method | TRIzol-style lysis (Buffer RL) + silica spin-column purification |
| Sample types | Tissues 50–100 mg, adherent or suspension cells |
| Elution | 30–50 µl |
| Storage / shipping | Buffer RL at 4 °C; ambient shipping |
Like-for-like option: CHANGYU TRIpure Reagent (CYRN01)
If you use TriPure or TRIzol as a liquid reagent and want to keep the same workflow, the direct match is CHANGYU TRIpure Reagent (CYRN01): a monophasic phenol–guanidine reagent that isolates total RNA, DNA and protein from one sample. If you prefer to avoid the chloroform phase separation, CYRN03 combines TRIzol-style lysis with a spin column.
| TriPure (Roche) | CHANGYU TRIpure (CYRN01) | CYRN03 RNApure kit | |
|---|---|---|---|
| Format | Liquid monophasic reagent | Liquid monophasic reagent | Lysis buffer + silica spin column |
| Chemistry | Phenol + guanidine thiocyanate | Phenol + guanidine | TRIzol-style lysis (Buffer RL), column purification |
| Isolates | RNA, DNA, protein | RNA, DNA, protein | Total RNA |
| Samples | Tissues, cells | Animal and plant tissue, cells, bacteria | Tissues 50–100 mg, cells |
| Pack sizes | Quoted by Roche catalog number | CYRN0101 = 50 mL, CYRN0102 = 100 mL | See product page |
| RNA purity | Per manufacturer | A260/A280 ≥ 1.8 in TE | Per manual |
Both TriPure (Roche) and the Changyu options can be quoted on one list. Request a CYRN01 quotation · TRIzol alternative overview. Research use only.
Frequently asked questions
- Do you stock TriPure (Roche) or TRIzol (Thermo Fisher)? Send the catalog number and quantity — we check availability through verified China supply channels and quote competitive options, including our own CYRN03 RNApure kit.
- What is the difference between TriPure and TRIzol? Same monophasic phenol–guanidine chemistry family, different brands. Both isolate RNA (plus DNA and protein) from a single sample; follow the manufacturer protocol for each.
- Is CYRN03 the same as TriPure? Not the same product — CYRN03 uses TRIzol-style lysis (Buffer RL) combined with silica spin columns instead of the classic chloroform phase separation. Comparable input: tissues 50–100 mg or cultured cells.
- Can you quote “tripure r60” or a specific formulation? We do not publish third-party catalog interpretations. Tell us the exact catalog number or your application (tissue/cell type, expected RNA yield) and we confirm the right option.
- Is this for clinical use? No — all products are Research Use Only (RUO). Not for diagnostic, therapeutic, or clinical use.
Request a quote
Send the catalog number you need (e.g. TriPure/TRIzol numbers or CYRN03), quantity, and destination city. Changyu Bio replies with lead time and a commercial quotation.
Request a quote for RNA isolation reagents · CYRN03 RNApure product page · All RNA & DNA extraction kits
TriPure is a trademark of Roche; TRIzol is a trademark of Thermo Fisher Scientific. This page is for catalog matching and research quotation only. Specifications follow the CYRN03 product page; re-check before the purchase order. All products RUO — not for diagnostic, therapeutic, or clinical use.