Looking for a NanoDrop alternative? CHANGYU MALL offers micro-volume UV-Vis spectrophotometers that read DNA, RNA and protein from 0.5–4 µL, with A260/A280 and A260/A230 purity ratios on screen. They are cost-effective options from the China supply chain, quoted together with your other lab items.
Micro-volume spectrophotometers in CHANGYU MALL
Micro-Volume UV-Vis Spectrophotometers (from 0.5 µL)
- 200–900 nm; xenon lamp with CMOS linear image sensor
- Micro-volume and cuvette modes on selected models
- Tablet touch control; audit trail and user permissions
Micro-Volume UV-Vis Spectrophotometer, 4 Path Lengths
- 4-pathlength detection technology
- Built-in printer
- High repeatability; wide concentration range
Model options at a glance
| Item No. | Path length | Sample volume | Detector | Cuvette mode |
|---|---|---|---|---|
| CY-SPC-01A | 1 mm | 4 µL | 1024-pixel CMOS | — |
| CY-SPC-01B | 1 mm | 4 µL | 2048-pixel CMOS | Yes |
| CY-SPC-01C | 1 / 0.5 / 0.05 mm | 0.5–5 µL | 2048-pixel CMOS | — |
| CY-SPC-01D | 1 / 0.5 / 0.05 mm, automatic | 0.5–5 µL | 2048-pixel CMOS | Yes |
| CY-SPC-01E | 1 / 0.5 / 0.1 / 0.05 / 0.02 mm, automatic | 0.5–4 µL | 4096-pixel CMOS | — |
| CY-SPC-01F | 1 / 0.5 / 0.1 / 0.05 / 0.02 mm, automatic | 0.5–4 µL | 4096-pixel CMOS | Yes |
| CY-INS-04 | 4 path lengths | Micro-volume | See data sheet | See data sheet |
What to compare when you choose a micro-volume spectrophotometer
- Path lengths. More path lengths (switched automatically) let one drop cover both dilute and concentrated samples without dilution.
- Sample volume. 0.5–1 µL matters when your RNA or protein is precious.
- Wavelength range. 200–900 nm covers nucleic acids (260 nm), protein (280 nm), contaminants (230 nm) and labelled dyes.
- Cuvette mode. Useful for OD600 and for samples you prefer to read in a standard cell.
- Data handling. Touch-screen software, export, user permissions and audit trail if your lab works under GLP.
Reading the numbers correctly
An A260/A280 near 2.0 is expected for pure RNA and near 1.8 for pure DNA, and a low A260/A230 points to salt, guanidine or phenol carry-over. A good ratio does not prove RNA is intact – check integrity on a gel or by RIN. See our guides: why an A260/A280 of 1.8 is not a purity pass, RNA quality reference values and reading 28S and 18S on a gel.
How ordering works
- Single units are welcome; there is no minimum order quantity.
- Equipment, kits and global-brand items can be combined on one quotation and one shipment.
- Payment by bank transfer (T/T) in USD to our company account.
- Power supply (voltage and plug), shipping method, lead time and export documents are confirmed with each quotation.
Frequently asked questions
Is this a NanoDrop?
No. NanoDrop is a trademark of Thermo Fisher Scientific. The instruments on this page are independent micro-volume spectrophotometers and are not made by or affiliated with Thermo Fisher. Compare the specifications against your application before you order; we can send the data sheet first.
Can it measure A260/A280 and A260/A230?
Yes. The CY-SPC-01 series covers 200–900 nm, which includes 230, 260 and 280 nm, so you can read nucleic acid concentration and the A260/A280 and A260/A230 purity ratios.
How much sample do I need?
Depending on the model, 0.5–4 µL per measurement. Models with automatic path-length switching accept 0.5–5 µL or 0.5–4 µL; the single 1 mm path-length models use 4 µL.
Can I also measure in a cuvette?
Yes, on the models listed with cuvette mode (CY-SPC-01B, 01D and 01F). Use it for diluted samples or cell-culture OD600 readings.
Can I order just one instrument?
Yes. Single units are welcome. Power supply, shipping method and lead time are confirmed with your quotation.
NanoDrop is a trademark of Thermo Fisher Scientific. CHANGYU MALL products are not affiliated with Thermo Fisher. For research and laboratory use.
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